How hyaluronic acid reverses photoaging

The production of new collagen appears to stimulate the infusion of the most popular type of filler, acid (CL-HA), according to one published in Experimental Dermatology. Practically this means that it can reverse the skin changes associated with photoaging. This injectable substance is already widely used in cosmetic medicine for “filling” thin and deep wrinkles and grinding the scars, for correcting the facial contour and strengthening cheekbones, as well as for correcting the nose shape and adding volume to the lips. This study showed that hyaluronic acid not only “fills” but also stimulates the production of new collagen and indeed very quickly. “When the skin has been exposed for years to the sun and UV radiation emitted from artificial tanning beds (the spectrum of which is similar to that of the sun) suffers damage perceived by the appearance of wrinkles, relaxation, paleness, discoloration, as well as by the change of its texture. These characteristics make up the so-called photo-aging skin and are made up of changes in the chrome. The chrome is under the skin, and is formed, in addition, by elastin and a network of collagen fibers, which support the skin and give it flexibility. When it grows prematurely these fibers break and thus the skin loses its youthful appearance,” explains Dermatologist – Afrodisiologist Dr. Christos Stamos. In order to investigate the course and changes caused by the infusion of hyaluronic acid into the skin, American researchers, from the University of Michigan Dermatological Department, injected hyaluronic acid (CL-HA) into photo-aging skin of the antibrace of people over 60 and received skin samples at various times. Evaluating biopsies, the scientific group examined the time of onset of elongation and activation of fibroblasts (the collagen producing cells), as well as the duration and mechanisms under which these changes occur. It also assessed whether the activation of fibroblasts led to collagen deposition. Previous studies have found that the infusion of hyaluronic acid into photo-aging skin can reverse changes in collagen and its fibroblasts, “inducing” them to synthesize collagen, but had not been investigated if the “fresh” collagen is converted into an entire collagen network. Researchers noted that hyaluronic acid injections rapidly (up to 1 week) and continuously (for 6-9 months) stimulate fibroblasts, which make up dense and thick collagen bundles 4 weeks after injection and continue for at least 12 months. These findings show, in other words, how this particular filler improves skin appearance in the short term and in addition, since the newly formed collagen lasts many years, they give an insight into how it can lead to long-term skin improvement, for months or even a year after treatment. “The aging of human skin is a complex biological process, the result of two biologically independent processes, natural aging and that due to external factors, namely ultraviolet radiation. About 80% of facial skin aging is attributed to it and is directly related to loss of moisture. Hyaluronic acid is the basic molecule involved in its preservation, since it has the unique ability to attract and bind water. Over time, its ability is gradually lost and thus the skin “cleans up” becomes dry and wrinkled. In recent years we have been able to make up for it with synthetic hyaluronic acid. When inserted into the desired parts of the skin of the face, with extremely thin needles, it fills the space between collagen and elastin fibers, filling in the lost natural tumor. It is an extremely simple, fast and absolutely safe treatment, with immediate results and zero recovery time. It is most commonly preferred for filling the wrinkles of the forehead, mesophryus, lips, eyes, throat and rhinoparean grooves (laughs wrinkles). It adds volume to the cheekbones, illuminates the black circles of the eyes, forms juicy and perfectly formed (as desired) lips and corrects the shape of the nose, giving beauty and harmony to the face. It doesn’t cause side effects except mild bruising and swelling that disappear in a few days. Treatment, however, must be applied by an experienced dermatologist to avoid any infections or lumps due to uneven placement of the material. But even in this case, there must be no concern, because the result can be reversed immediately. Hyaluronic acid is a malleable material that can turn time back – correct imperfections, enhance the beautiful facial characteristics, make up the volume and restore lost elasticity to the skin,” Dr Stamos concludes.