Bryan Johnson: Anti-aging guru stopped the drug he was taking for years due to wrinkles

He has become known as the “guru of aging” – the reason for Bryan Johnson, who “swallows” about 54 pills for breakfast to reverse it, recently discovered a wrinkle in his meticulous method to avoid death. Zambrich Bryan Johnson, a technology tycoon who has been set to reverse the aging process by spending millions annually, consumes every two weeks 13 milligrams of the immunosuppressive rapamicin, which patients receive by transplant to prevent organ rejection. CORVERSE The U.S. Food and Drug Organization has however not approved rapamycin for anti-aging treatment, but doctors prescribe it because it has been shown to prolong the healthy life of mice. In a new Netflix documentary for him, titled “Don’t Die: The Man Who Wants to Live Forever”, Johnson called his routine “the most aggressive rapamycin protocol than anyone else in the industry”. CORVERSE But shortly after filming the documentary, he confessed that he stopped taking rapamycin – and that he might have done more harm than good. “ I accept it because there are probably some long – lived benefits, ” Johnson says in the film. “It’s the kind of thing in the longevity community people are excited about,” he continued. “Out of the community of longevity, it’s still kind of crazy, as if you say, “Yes, I’m taking an immunosuppressive medicine”. People react… “Well, that’s weird and why would you ever do that?”. Johnson stressed that he experimented with rapamycin for almost five years, by the end of September. He admitted in November that he rejected the anticancer drug from his strict routine. “I have tried various rapamycin protocols, including weekly (5.6 and 10 mg doses), per two (13 mg) and alternate weekly (6/13 mg) to optimize rejuvenation and reduce side effects,” Johnson told X, writes the New York Post. On September 28th, I decided to stop rapamycin, ending already 5 years of experience with this mole for its longevity potential. I have tested various rapamycin protocols including weekly (5, 6, and 10 mg dose schedules), biweekly (13 mg) and alternativeing weekly (6/13mg)… — Bryan Johnson /dd (@bryan_johnson) “Despite the enormous potential of preclinical trials, my group and I concluded that the benefits of the lifelong dose of rapamycin do not justify the severe side effects,” he added. Johnson said he experienced occasional skin and soft tissue infections, abnormal levels of fat in his blood, increased blood sugar and higher heart rate of calm. “Without identifying other underlying causes, we suspected rapamycin and because dosage adjustments had no effect, we decided to stop it altogether,” he explained. View this post on Instagram Medical experts appearing in Netflix’s documentary shared their concerns about people getting this ingredient – first isolated in soil collected from Easter Island in the 1960s – for long life. Because rapamycin suppresses the immune system, “adverse effects may include very dangerous bacterial infections, such as pneumonia or pharyngitis,” said Dr. Oliver Zolman, a long-lived physician working with Johnson. View this post on Instagram Dr Vadim Gladyshev, a medical professor at Harvard Medical School, said that “correctly designed experiments” should be done to test the effectiveness of rapamycin in slowing down human aging.